MeSsy with Christina Applegate & Jamie-Lynn Sigler

Wishbone Production

On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Read more

Society & Culture Comedy

Episodes

Olivia Munn

03/24/2026 01:10:51Carl Radke

03/17/2026 01:16:28 How to Heal Your Relationship With Life

03/10/2026 01:14:48We Don’t Want to Be Defined by This

03/03/2026 00:41:46Kelly Ripa

02/24/2026 01:04:25 Show all episodes

Our take on MeSsy with Christina Applegate & Jamie-Lynn Sigler podcast

Messy brings Christina Applegate and Jamie-Lynn Sigler together in an honest, weekly chat about living with multiple sclerosis. As celebrated actresses who share this personal battle, they offer knowledge and support to others facing similar struggles. Their open discussions give comfort and company to those dealing with life's challenging moments and strength in shared experiences. MeSsy with Christina Applegate & Jamie-Lynn Sigler is a personal journals podcast by Wishbone Production.